
Sirena Irwin
Biography
Sirena grew up around the U.S. and abroad her mother, Margaret Irwin-Brandon, is a harpsichordist and conductor of a Baroque Orchestra, and her father, John Irwin, was a physicist (with a significant stint as a dropped out hippie)-landed ultimately at Sanford University. After time spent at Northfield Mt. Hermon boarding school where she fell in love with theater, she attended San Francisco State University and graduated with degrees in Theater and International Relations. After a successful stint in a popular San Francisco sketch comedy group, she landed in Los Angeles where her knack for voices and accents were quickly put to use in the world of animation. This ultimately brought her to her successful career as a voice director in animation (thanks to her mentor Andrea Romano!) garnering her an Emmy nomination in 2021.
Also Known As
Movie Appearances

Can I Be Your Bratwurst, Please?
2008

Electric Apricot
as The Photographer
2007

The SpongeBob SquarePants Movie
as Reporter / Driver / Ice Cream Lady (voice)
2004

Planes
as Additional Voices (voice)
2013
The Longer Day of Happiness
as Alisa
2012

The Sky is Falling
as Gabby
2001

Superman: Unbound
as Alura (voice)
2013

Justice League: Throne of Atlantis
as Queen Atlanna (voice)
2015

Vitaminamulch: Air Spectacular
as Additional Voice
2014

The SpongeBob Movie: Sponge Out of Water
as Computer Voice / Shocked Mob Member (voice)
2015

Spongebob’s Runaway Roadtrip
as Margret SquarePants
2011

Holly Hobbie and Friends: Christmas Wishes
as Mrs. Palmer (voice)
2006

The Trip
as Beverly
2002
A Man Alone
as Therapist
2024

Batman: Return of the Caped Crusaders
as Miranda Moore (voice)
2016

Batman vs. Two-Face
as Harleen Quinzel (voice)
2017

SpongeBob Squarepants: Kreepaway Kamp
as Lady Upturn / Nurse Helga / Mo / Teen Girls (voice)
2024

SpongeBob LongPants
as Fancy Lady Fish / Kid Fish (voice)
2016
SpongeBob’s Big Birthday Blowout
as SpongeBob’s Mom / Gawky Female / The Kid / Office Worker
2019

SpongeBob and Patrick's Timeline Twist-Up
as Pffht / Various Incidental Characters (voice)
2025
TV Appearances

Ellen
as Cherry-O
1994

Stripperella
as Persephone (voice)
2003

The Patrick Star Show
as Elder Woman / Fly Dancers / Crowd / Dancers (voice)
2021

The Patrick Star Show
as Twin Mom / Toddler 3 / Toddlers / Parents (voice)
2021

The Patrick Star Show
as Go Girl / Go Woman (voice)
2021

We Baby Bears
as Guard #1 / Old Lady Bug / Poochy (voice)
2022

We Baby Bears
as Mayor Centipede / Silk Worms / Mom (voice)
2022

We Baby Bears
as Baba Yaga House / Baby Baba Yaga House (voice)
2022

SpongeBob SquarePants
as Margaret SquarePants (voice)
1999

We Baby Bears
as Reporter / Mayor / Unica's Gut (voice)
2022

The Mighty Ones
as The Queen (voice)
2020

Apple & Onion
as The Eater (voice)
2018